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Nyomja le Decimális Kék overall mutation load and p53 mutations meghal Hirhedt vezérlő

TP53 mutational landscape of metastatic head and neck cancer reveals  patterns of mutation selection - eBioMedicine
TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection - eBioMedicine

Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule  Stabilizers: the Y220X Paradigm | ACS Chemical Biology
Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm | ACS Chemical Biology

Mutational processes shape the landscape of TP53 mutations in human cancer  | Nature Genetics
Mutational processes shape the landscape of TP53 mutations in human cancer | Nature Genetics

A TP53-Associated Immune Prognostic Signature for the Prediction of Overall  Survival and Therapeutic Responses in Muscle-Invasive Bladder Cancer -  Frontiers
A TP53-Associated Immune Prognostic Signature for the Prediction of Overall Survival and Therapeutic Responses in Muscle-Invasive Bladder Cancer - Frontiers

Homogenous TP53mut-associated tumor biology across mutation and cancer  types revealed by transcriptome analysis | Cell Death Discovery
Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by transcriptome analysis | Cell Death Discovery

Low-burden TP53 mutations in CLL: clinical impact and clonal evolution  within the context of different treatment options - ScienceDirect
Low-burden TP53 mutations in CLL: clinical impact and clonal evolution within the context of different treatment options - ScienceDirect

Frontiers | Promising New Tools for Targeting p53 Mutant Cancers: Humoral  and Cell-Based Immunotherapies
Frontiers | Promising New Tools for Targeting p53 Mutant Cancers: Humoral and Cell-Based Immunotherapies

Diverse rescue potencies of p53 mutations to ATO are predetermined by  intrinsic mutational properties | Science Translational Medicine
Diverse rescue potencies of p53 mutations to ATO are predetermined by intrinsic mutational properties | Science Translational Medicine

Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome:  Cell
Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome: Cell

Survival of patients with p53 mutations in the DNA-binding motifs... |  Download Scientific Diagram
Survival of patients with p53 mutations in the DNA-binding motifs... | Download Scientific Diagram

TP53 mutational landscape of metastatic head and neck cancer reveals  patterns of mutation selection - eBioMedicine
TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection - eBioMedicine

Analysis of P53 mutations and their expression in 56 colorectal cancer cell  lines | PNAS
Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines | PNAS

Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell  Lymphoma | NEJM
Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell Lymphoma | NEJM

Acetylation halts missense mutant p53 aggregation and rescues tumor  suppression in non-small cell lung cancers - ScienceDirect
Acetylation halts missense mutant p53 aggregation and rescues tumor suppression in non-small cell lung cancers - ScienceDirect

TP53 mutations predict poor response to immunotherapy in patients with  metastatic solid tumors - Kim - 2023 - Cancer Medicine - Wiley Online  Library
TP53 mutations predict poor response to immunotherapy in patients with metastatic solid tumors - Kim - 2023 - Cancer Medicine - Wiley Online Library

TP53 mutation spectrum in primary colorectal cancers. a Proportion of... |  Download Scientific Diagram
TP53 mutation spectrum in primary colorectal cancers. a Proportion of... | Download Scientific Diagram

Implications of driver genes associated with a high tumor mutation burden  identified using next‑generation sequencing on immunotherapy in  hepatocellular carcinoma
Implications of driver genes associated with a high tumor mutation burden identified using next‑generation sequencing on immunotherapy in hepatocellular carcinoma

IJMS | Free Full-Text | Do Mutations Turn p53 into an Oncogene?
IJMS | Free Full-Text | Do Mutations Turn p53 into an Oncogene?

Mutant p53 elicits context-dependent pro-tumorigenic phenotypes | Oncogene
Mutant p53 elicits context-dependent pro-tumorigenic phenotypes | Oncogene

Probability Distributions of p53 Mutations and Their Corresponding Shannon  Entropies in Different Cancer Cell Types | SpringerLink
Probability Distributions of p53 Mutations and Their Corresponding Shannon Entropies in Different Cancer Cell Types | SpringerLink

LRP1B or TP53 mutations are associated with higher tumor mutational burden  and worse survival in hepatocellular carcinoma
LRP1B or TP53 mutations are associated with higher tumor mutational burden and worse survival in hepatocellular carcinoma

Prognostic value of TP53 mutation location in breast cancer | CMAR
Prognostic value of TP53 mutation location in breast cancer | CMAR

p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?
p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?

Omics analyses of a somatic Trp53R245W/+ breast cancer model identify  cooperating driver events activating PI3K/AKT/mTOR signaling | PNAS
Omics analyses of a somatic Trp53R245W/+ breast cancer model identify cooperating driver events activating PI3K/AKT/mTOR signaling | PNAS

p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?
p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?

Frequency of p53 mutations in human cancers. (A) Schematic picture... |  Download Scientific Diagram
Frequency of p53 mutations in human cancers. (A) Schematic picture... | Download Scientific Diagram